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Crystal structure of the RNA demethylase ALKBH5 from zebrafish

ALKBH5, a member of AlkB family proteins, has been reported as a mammalian N(6)-methyladenosine (m(6)A) RNA demethylase. Here we report the crystal structure of zebrafish ALKBH5 (fALKBH5) with the resolution of 1.65 Å. Structural superimposition shows that fALKBH5 is comprised of a conserved jelly-r...

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Detalhes bibliográficos
Main Authors: Chen, Weizhong, Zhang, Liang, Zheng, Guanqun, Fu, Ye, Ji, Quanjiang, Liu, Fange, Chen, Hao, He, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982313/
https://ncbi.nlm.nih.gov/pubmed/24561204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.02.021
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