NANOG Amplifies STAT3 Activation and They Synergistically Induce the Naive Pluripotent Program

Reprogramming of a differentiated cell back to a naive pluripotent identity is thought to occur by several independent mechanisms. Two such mechanisms include NANOG and activated STAT3 (pSTAT3), known master regulators of naive pluripotency acquisition [1–5]. Here, we investigated the relationship b...

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Main Authors: Stuart, Hannah T., van Oosten, Anouk L., Radzisheuskaya, Aliaksandra, Martello, Graziano, Miller, Anzy, Dietmann, Sabine, Nichols, Jennifer, Silva, José C.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982126/
https://ncbi.nlm.nih.gov/pubmed/24462001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2013.12.040
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