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Modeling CaMKII-mediated regulation of L-type Ca(2+) channels and ryanodine receptors in the heart
Excitation-contraction coupling (ECC) in the cardiac myocyte is mediated by a number of highly integrated mechanisms of intracellular Ca(2+) transport. Voltage- and Ca(2+)-dependent L-type Ca(2+) channels (LCCs) allow for Ca(2+) entry into the myocyte, which then binds to nearby ryanodine receptors...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3982069/ https://ncbi.nlm.nih.gov/pubmed/24772082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00060 |
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