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CaMKII-Induced Shift in Modal Gating Explains L-Type Ca(2+) Current Facilitation: A Modeling Study
Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) plays an important role in L-type Ca(2+) channel (LCC) facilitation: the Ca(2+)-dependent augmentation of Ca(2+) current (I(CaL)) exhibited during rapid repeated depolarization. Multiple mechanisms may underlie facilitation, including an increas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2717283/ https://ncbi.nlm.nih.gov/pubmed/19254537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.055 |
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