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Modeling CaMKII-mediated regulation of L-type Ca(2+) channels and ryanodine receptors in the heart

Excitation-contraction coupling (ECC) in the cardiac myocyte is mediated by a number of highly integrated mechanisms of intracellular Ca(2+) transport. Voltage- and Ca(2+)-dependent L-type Ca(2+) channels (LCCs) allow for Ca(2+) entry into the myocyte, which then binds to nearby ryanodine receptors...

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Hlavní autoři: Greenstein, Joseph L., Foteinou, Panagiota T., Hashambhoy-Ramsay, Yasmin L., Winslow, Raimond L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3982069/
https://ncbi.nlm.nih.gov/pubmed/24772082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00060
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