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CaMKII-dependent Activation of Late I(Na) Contributes to Cellular Arrhythmia in a Model of the Cardiac Myocyte
Cardiac voltage-gated Na(+) channels underlie membrane depolarization during the upstroke of the action potential (AP). These channels also exhibit a late, slowly-inactivating component of current (late I(Na)) that may be enhanced under pathological conditions such as heart failure, and may therefor...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517881/ https://ncbi.nlm.nih.gov/pubmed/22255378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/IEMBS.2011.6091155 |
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