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The Role of Stochastic and Modal Gating of Cardiac L-Type Ca(2+) Channels on Early After-Depolarizations

Certain signaling events that promote L-type Ca(2+) channel (LCC) phosphorylation, such as β-adrenergic stimulation or an increased expression of Ca(2+)/calmodulin-dependent protein kinase II, promote mode 2 gating of LCCs. Experimental data suggest the hypothesis that these events increase the like...

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Hlavní autoři: Tanskanen, Antti J., Greenstein, Joseph L., O'Rourke, Brian, Winslow, Raimond L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2005
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201453/
https://ncbi.nlm.nih.gov/pubmed/15501946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051508
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