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Coregulator Control of Androgen Receptor Action by a Novel Nuclear Receptor-binding Motif
The androgen receptor (AR) is a ligand-activated transcription factor that is essential for prostate cancer development. It is activated by androgens through its ligand-binding domain (LBD), which consists predominantly of 11 α-helices. Upon ligand binding, the last helix is reorganized to an agonis...
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979403/ https://ncbi.nlm.nih.gov/pubmed/24523409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534859 |
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