The Oncoprotein BCL11A Binds to Orphan Nuclear Receptor TLX and Potentiates its Transrepressive Function

Nuclear orphan receptor TLX (NR2E1) functions primarily as a transcriptional repressor and its pivotal role in brain development, glioblastoma, mental retardation and retinopathologies make it an attractive drug target. TLX is expressed in the neural stem cells (NSCs) of the subventricular zone and...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Estruch, Sara B., Buzón, Víctor, Carbó, Laia R., Schorova, Lenka, Lüders, Jens, Estébanez-Perpiñá, Eva
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366998/
https://ncbi.nlm.nih.gov/pubmed/22675500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037963
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