Coregulator Control of Androgen Receptor Action by a Novel Nuclear Receptor-binding Motif

The androgen receptor (AR) is a ligand-activated transcription factor that is essential for prostate cancer development. It is activated by androgens through its ligand-binding domain (LBD), which consists predominantly of 11 α-helices. Upon ligand binding, the last helix is reorganized to an agonis...

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Bibliographische Detailangaben
Hauptverfasser: Jehle, Katja, Cato, Laura, Neeb, Antje, Muhle-Goll, Claudia, Jung, Nicole, Smith, Emmanuel W., Buzon, Victor, Carbó, Laia R., Estébanez-Perpiñá, Eva, Schmitz, Katja, Fruk, Ljiljana, Luy, Burkhard, Chen, Yu, Cox, Marc B., Bräse, Stefan, Brown, Myles, Cato, Andrew C. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979403/
https://ncbi.nlm.nih.gov/pubmed/24523409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534859
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