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Regeneration of the aged thymus by a single transcription factor

Thymic involution is central to the decline in immune system function that occurs with age. By regenerating the thymus, it may therefore be possible to improve the ability of the aged immune system to respond to novel antigens. Recently, diminished expression of the thymic epithelial cell (TEC)-spec...

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Detalhes bibliográficos
Main Authors: Bredenkamp, Nicholas, Nowell, Craig S., Blackburn, C. Clare
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978836/
https://ncbi.nlm.nih.gov/pubmed/24715454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103614
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