Single epicardial cell transcriptome sequencing identifies Caveolin 1 as an essential factor in zebrafish heart regeneration

In contrast to mammals, adult zebrafish have a high capacity to regenerate damaged or lost myocardium through proliferation of cardiomyocytes spared from damage. The epicardial sheet covering the heart is activated by injury and aids muscle regeneration through paracrine effects and as a multipotent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Development
Hauptverfasser: Cao, Jingli, Navis, Adam, Cox, Ben D., Dickson, Amy L., Gemberling, Matthew, Karra, Ravi, Bagnat, Michel, Poss, Kenneth D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
Schlagworte:
Stem Cells and Regeneration
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725347/
https://ncbi.nlm.nih.gov/pubmed/26657776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.130534
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