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Regeneration of the aged thymus by a single transcription factor

Thymic involution is central to the decline in immune system function that occurs with age. By regenerating the thymus, it may therefore be possible to improve the ability of the aged immune system to respond to novel antigens. Recently, diminished expression of the thymic epithelial cell (TEC)-spec...

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Bibliographic Details
Main Authors: Bredenkamp, Nicholas, Nowell, Craig S., Blackburn, C. Clare
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978836/
https://ncbi.nlm.nih.gov/pubmed/24715454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103614
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