Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor

Terminally differentiated post-mitotic cells are generally considered irreversibly developmentally locked, i.e. incapable of being reprogrammed in vivo into entirely different cell types. We found that brief expression of a single transcription factor, the ELT-7 GATA factor, can convert the identity...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Riddle, Misty R., Weintraub, Abraham, Nguyen, Ken C. Q., Hall, David H., Rothman, Joel H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2013
Gaiak:
Stem Cells and Regeneration
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848185/
https://ncbi.nlm.nih.gov/pubmed/24257624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103010
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