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Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor
Terminally differentiated post-mitotic cells are generally considered irreversibly developmentally locked, i.e. incapable of being reprogrammed in vivo into entirely different cell types. We found that brief expression of a single transcription factor, the ELT-7 GATA factor, can convert the identity...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Company of Biologists
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3848185/ https://ncbi.nlm.nih.gov/pubmed/24257624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.103010 |
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