No Impact of Lentiviral Transduction on Hematopoietic Stem/Progenitor Cell Telomere Length or Gene Expression in the Rhesus Macaque Model

The occurrence of clonal perturbations and leukemia in patients transplanted with gamma-retroviral (RV) vector–transduced autologous hematopoietic stem and progenitor cells (HSPCs) has stimulated extensive investigation, demonstrating that proviral insertions may perturb adjacent proto-oncogene expr...

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Hlavní autoři: Sellers, Stephanie E, Dumitriu, Bogdan, Morgan, Mary J, Hughes, William M., Wu, Colin O, Raghavarchari, Nalini, Yang, Yanqin, Uchida, Naoya, Tisdale, John F, An, Dong S, Chen, Irvin S, Hematti, Peiman, Donahue, Robert E, LaRochelle, Andre, Young, Neal S, Calado, Rodrigo T, Dunbar, Cynthia E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978805/
https://ncbi.nlm.nih.gov/pubmed/23863881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.168
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