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No Impact of Lentiviral Transduction on Hematopoietic Stem/Progenitor Cell Telomere Length or Gene Expression in the Rhesus Macaque Model
The occurrence of clonal perturbations and leukemia in patients transplanted with gamma-retroviral (RV) vector–transduced autologous hematopoietic stem and progenitor cells (HSPCs) has stimulated extensive investigation, demonstrating that proviral insertions may perturb adjacent proto-oncogene expr...
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| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978805/ https://ncbi.nlm.nih.gov/pubmed/23863881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.168 |
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