Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas

Background: Epidermal growth factor receptor is overexpressed in most pediatric high-grade gliomas (HGG). Since erlotinib had shown activity in adults with HGG, we conducted a phase II trial of erlotinib and local radiotherapy (RT) in children with newly diagnosed HGG. Methods: Following maximum sur...

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Bibliografske podrobnosti
Main Authors: Qaddoumi, Ibrahim, Kocak, Mehmet, Pai Panandiker, Atmaram S., Armstrong, Gregory T., Wetmore, Cynthia, Crawford, John R., Lin, Tong, Boyett, James M., Kun, Larry E., Boop, Fredrick A., Merchant, Thomas E., Ellison, David W., Gajjar, Amar, Broniscer, Alberto
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Oncology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978340/
https://ncbi.nlm.nih.gov/pubmed/24744992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00067
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