Phase II Trial of Erlotinib during and after Radiotherapy in Children with Newly Diagnosed High-Grade Gliomas

Background: Epidermal growth factor receptor is overexpressed in most pediatric high-grade gliomas (HGG). Since erlotinib had shown activity in adults with HGG, we conducted a phase II trial of erlotinib and local radiotherapy (RT) in children with newly diagnosed HGG. Methods: Following maximum sur...

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Detalhes bibliográficos
Main Authors: Qaddoumi, Ibrahim, Kocak, Mehmet, Pai Panandiker, Atmaram S., Armstrong, Gregory T., Wetmore, Cynthia, Crawford, John R., Lin, Tong, Boyett, James M., Kun, Larry E., Boop, Fredrick A., Merchant, Thomas E., Ellison, David W., Gajjar, Amar, Broniscer, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978340/
https://ncbi.nlm.nih.gov/pubmed/24744992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2014.00067
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