Phase I and Pharmacokinetic Studies of Erlotinib Administered Concurrently With Radiotherapy for Children, Adolescents, and Young Adults with High-Grade Glioma

STATEMENT OF TRANSLATIONAL RELEVANCE: Although chemotherapy has been used in most clinical trials for children with high-grade glioma, no drug regimen has so far stood out as particularly beneficial for these patients. Based on pre-clinical and clinical experience in adults with similar tumors, we r...

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Hauptverfasser: Broniscer, Alberto, Baker, Suzanne J., Stewart, Clinton F., Merchant, Thomas E., Laningham, Fred H., Schaiquevich, Paula, Kocak, Mehmet, Morris, E. Brannon, Endersby, Raelene, Ellison, David W., Gajjar, Amar
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629527/
https://ncbi.nlm.nih.gov/pubmed/19147777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1923
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