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Arsenic trioxide inhibits Hedgehog, Notch and stem cell properties in glioblastoma neurospheres
BACKGROUND: Notch and Hedgehog signaling have been implicated in the pathogenesis and stem-like characteristics of glioblastomas, and inhibitors of the pathways have been suggested as new therapies for these aggressive tumors. It has also been reported that targeting both pathways simultaneously can...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977902/ https://ncbi.nlm.nih.gov/pubmed/24685274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2051-5960-2-31 |
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