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Targeting Notch Signaling and Autophagy Increases Cytotoxicity in Glioblastoma Neurospheres

Glioblastomas are highly aggressive tumors that contain treatment resistant stem‐like cells. Therapies targeting developmental pathways such as Notch eliminate many neoplastic glioma cells, including those with stem cell features, but their efficacy can be limited by various mechanisms. One potentia...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Natsumeda, Manabu, Maitani, Kosuke, Liu, Yang, Miyahara, Hiroaki, Kaur, Harpreet, Chu, Qian, Zhang, Hongyan, Kahlert, Ulf D., Eberhart, Charles G.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8029219/
https://ncbi.nlm.nih.gov/pubmed/26613556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12343
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