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Molecular analysis of functional redundancy among anti-apoptotic Bcl-2 proteins and its role in cancer cell survival
Bcl-2 family proteins act as essential regulators and mediators of intrinsic apoptosis. Several lines of evidence suggest that the anti-apoptotic members of the family, including Bcl-2, Bcl-xL and Mcl-1, exhibit functional redundancy. However, the current evidence is largely indirect, and based main...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977614/ https://ncbi.nlm.nih.gov/pubmed/24556425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.02.010 |
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