Laddar...

Bcl-xL promotes metastasis independent of its anti-apoptotic activity

Bcl-xL suppresses mitochondria-mediated apoptosis and is frequently overexpressed in cancer to promote cancer cell survival. Bcl-xL also promotes metastasis. However, it is unclear whether this metastatic function is dependent on its anti-apoptotic activity in the mitochondria. Here we demonstrate t...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Choi, Soyoung, Chen, Zhengming, Tang, Laura H., Fang, Yuanzhang, Shin, Sandra J., Panarelli, Nicole C., Chen, Yao-Tseng, Li, Yi, Jiang, Xuejun, Du, Yi-Chieh Nancy
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4735924/
https://ncbi.nlm.nih.gov/pubmed/26785948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10384
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!