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Functional impact of cancer patient‐associated Bcl‐xL mutations
Bcl‐xL, an antiapoptotic protein, is frequently overexpressed in cancer to promote survival of tumor cells. However, we have previously shown that Bcl‐xL promotes migration, invasion, and metastasis independent of its antiapoptotic function in mitochondria. The pro‐metastatic function of Bcl‐xL may...
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| Publicado no: | MedComm (2020) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8302207/ https://ncbi.nlm.nih.gov/pubmed/34308416 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mco2.36 |
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