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Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion

Tumors develop through multiple stages, implicating multiple effectors, but the tools to assess how candidate genes contribute to stepwise tumor progression have been limited. We have developed a novel system in which progression of phenotypes in a mouse model of pancreatic islet cell tumorigenesis...

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Sonraí Bibleagrafaíochta
Main Authors: Du, Yi-Chieh Nancy, Lewis, Brian C, Hanahan, Douglas, Varmus, Harold
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2007
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2020504/
https://ncbi.nlm.nih.gov/pubmed/17941720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050276
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