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Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion

Tumors develop through multiple stages, implicating multiple effectors, but the tools to assess how candidate genes contribute to stepwise tumor progression have been limited. We have developed a novel system in which progression of phenotypes in a mouse model of pancreatic islet cell tumorigenesis...

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Detalles Bibliográficos
Main Authors: Du, Yi-Chieh Nancy, Lewis, Brian C, Hanahan, Douglas, Varmus, Harold
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2020504/
https://ncbi.nlm.nih.gov/pubmed/17941720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050276
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