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Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic death
Microtubule inhibiting agents (MIAs) characteristically induce phosphorylation of the major anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2 and Bcl-xL, and although this leads to Mcl-1 degradation, the role of Bcl-2/Bcl-xL phosphorylation in mitotic death has remained controversial. This is in part...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824670/ https://ncbi.nlm.nih.gov/pubmed/24091677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.360 |
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