The anti-apoptotic Bcl-B protein inhibits BECN1-dependent autophagic cell death

Bcl-2 family members are key modulators of apoptosis that have recently been shown to also regulate autophagy. It has been previously reported that Bcl-2 and Bcl-X(L) bind and inhibit BECN1, an essential mediator of autophagy. Bcl-B is an anti-apoptotic member of the Bcl-2 family that possesses the...

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Autores principales: Robert, Guillaume, Gastaldi, Cecile, Puissant, Alexandre, Hamouda, Amine, Jacquel, Arnaud, Dufies, Maeva, Belhacene, Nathalie, Colosetti, Pascal, Reed, John C., Auberger, Patrick, Luciano, Fréderic
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
Materias:
Basic Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405843/
https://ncbi.nlm.nih.gov/pubmed/22498477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.19084
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