BH3 inhibitor sensitivity and Bcl-2 dependence in primary acute lymphoblastic leukemia cells

BH3 mimetic drugs may be useful to treat acute lymphoblastic leukemia (ALL) but the sensitivity of primary tumor cells has not been fully evaluated. Here B-lineage ALL cell cultures derived from a set of primary tumors were studied with respect to sensitivity to the BH3 mimetics ABT-263 and ABT-199...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cancer Res
Главные авторы: Alford, Sarah E., Kothari, Anisha, Loeff, Floris C., Eichhorn, Joshua M., Sakurikar, Nandini, Goselink, Henriette M., Saylors, Robert L., Jedema, Inge, Falkenburg, J.H. Frederik, Chambers, Timothy C.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383710/
https://ncbi.nlm.nih.gov/pubmed/25649768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-1849
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы