Loss of the GPI‐anchor in B‐lymphoblastic leukemia by epigenetic downregulation of PIGH expression

Adult B‐lymphoblastic leukemia (B‐ALL) is a hematological malignancy characterized by genetic heterogeneity. Despite successful remission induction with classical chemotherapeutics and novel targeted agents, enduring remission is often hampered by disease relapse due to outgrowth of a pre‐existing s...

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Détails bibliographiques
Publié dans:Am J Hematol
Auteurs principaux: Loeff, Floris C., Rijs, Kevin, van Egmond, Esther H. M., Zoutman, Willem H., Qiao, Xiaohang, Kroes, Wilhelmina G. M., Veld, Sabrina A. J., Griffioen, Marieke, Vermeer, Maarten H., Neefjes, Jacques, Frederik Falkenburg, J. H., Halkes, Constantijn J. M., Jedema, Inge
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Inc. 2018
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587464/
https://ncbi.nlm.nih.gov/pubmed/30370942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25337
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