Loss of the GPI‐anchor in B‐lymphoblastic leukemia by epigenetic downregulation of PIGH expression

Adult B‐lymphoblastic leukemia (B‐ALL) is a hematological malignancy characterized by genetic heterogeneity. Despite successful remission induction with classical chemotherapeutics and novel targeted agents, enduring remission is often hampered by disease relapse due to outgrowth of a pre‐existing s...

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Detalhes bibliográficos
Publicado no:Am J Hematol
Main Authors: Loeff, Floris C., Rijs, Kevin, van Egmond, Esther H. M., Zoutman, Willem H., Qiao, Xiaohang, Kroes, Wilhelmina G. M., Veld, Sabrina A. J., Griffioen, Marieke, Vermeer, Maarten H., Neefjes, Jacques, Frederik Falkenburg, J. H., Halkes, Constantijn J. M., Jedema, Inge
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6587464/
https://ncbi.nlm.nih.gov/pubmed/30370942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajh.25337
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