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cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex
The pattern of neurodegeneration in Alzheimer’s disease (AD) is very distinctive: neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau selectively affect pyramidal neurons of the aging association cortex that interconnect extensively through glutamate synapses on dendritic spines. In c...
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| Hauptverfasser: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977284/ https://ncbi.nlm.nih.gov/pubmed/24707050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322360111 |
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