cAMP-PKA phosphorylation of tau confers risk for degeneration in aging association cortex

The pattern of neurodegeneration in Alzheimer’s disease (AD) is very distinctive: neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau selectively affect pyramidal neurons of the aging association cortex that interconnect extensively through glutamate synapses on dendritic spines. In c...

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書誌詳細
主要な著者: Carlyle, Becky C., Nairn, Angus C., Wang, Min, Yang, Yang, Jin, Lu E., Simen, Arthur A., Ramos, Brian P., Bordner, Kelly A., Craft, George E., Davies, Peter, Pletikos, Mihovil, Šestan, Nenad, Arnsten, Amy F. T., Paspalas, Constantinos D.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2014
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977284/
https://ncbi.nlm.nih.gov/pubmed/24707050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322360111
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