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Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments

Intrinsically disordered proteins (IDPs) are involved in a wide range of regulatory processes in the cell. Owing to their flexibility, their conformations are expected to be particularly sensitive to the crowded cellular environment. Here we use single-molecule Förster resonance energy transfer to q...

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Bibliografische gegevens
Hoofdauteurs: Soranno, Andrea, Koenig, Iwo, Borgia, Madeleine B., Hofmann, Hagen, Zosel, Franziska, Nettels, Daniel, Schuler, Benjamin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977265/
https://ncbi.nlm.nih.gov/pubmed/24639500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1322611111
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