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Single-molecule spectroscopy reveals chaperone-mediated expansion of substrate protein
Molecular chaperones are an essential part of the machinery that avoids protein aggregation and misfolding in vivo. However, understanding the molecular basis of how chaperones prevent such undesirable interactions requires the conformational changes within substrate proteins to be probed during cha...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169939/ https://ncbi.nlm.nih.gov/pubmed/25165400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407086111 |
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