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Decameric SelA•tRNA(Sec) Ring Structure Reveals Mechanism of Bacterial Selenocysteine Formation
The 21st amino acid, selenocysteine (Sec), is synthesized on its cognate transfer RNA (tRNA(Sec)). In bacteria, SelA synthesizes Sec from Ser-tRNA(Sec), whereas in archaea and eukaryotes SepSecS forms Sec from phosphoserine (Sep) acylated to tRNA(Sec). We determined the crystal structures of Aquifex...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3976565/ https://ncbi.nlm.nih.gov/pubmed/23559248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1229521 |
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