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Dimer-dimer interaction of the bacterial selenocysteine synthase SelA promotes functional active site formation and catalytic specificity

The 21(st) amino acid, selenocysteine (Sec), is incorporated translationally into proteins, and is synthesized on its specific tRNA (tRNA(Sec)). In Bacteria, the selenocysteine synthase SelA converts Ser-tRNA(Sec), formed by seryl-tRNA synthetase, to Sec-tRNA(Sec). SelA, a member of the fold-type-I...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Itoh, Yuzuru, Bröcker, Markus J., Sekine, Shun-ichi, Söll, Dieter, Yokoyama, Shigeyuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306587/
https://ncbi.nlm.nih.gov/pubmed/24456689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.01.003
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