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Dimer-dimer interaction of the bacterial selenocysteine synthase SelA promotes functional active site formation and catalytic specificity

The 21(st) amino acid, selenocysteine (Sec), is incorporated translationally into proteins, and is synthesized on its specific tRNA (tRNA(Sec)). In Bacteria, the selenocysteine synthase SelA converts Ser-tRNA(Sec), formed by seryl-tRNA synthetase, to Sec-tRNA(Sec). SelA, a member of the fold-type-I...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Itoh, Yuzuru, Bröcker, Markus J., Sekine, Shun-ichi, Söll, Dieter, Yokoyama, Shigeyuki
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306587/
https://ncbi.nlm.nih.gov/pubmed/24456689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.01.003
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