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Decameric SelA•tRNA(Sec) Ring Structure Reveals Mechanism of Bacterial Selenocysteine Formation

The 21st amino acid, selenocysteine (Sec), is synthesized on its cognate transfer RNA (tRNA(Sec)). In bacteria, SelA synthesizes Sec from Ser-tRNA(Sec), whereas in archaea and eukaryotes SepSecS forms Sec from phosphoserine (Sep) acylated to tRNA(Sec). We determined the crystal structures of Aquifex...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Itoh, Yuzuru, Bröcker, Markus J., Sekine, Shun-ichi, Hammond, Gifty, Suetsugu, Shiro, Söll, Dieter, Yokoyama, Shigeyuki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976565/
https://ncbi.nlm.nih.gov/pubmed/23559248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1229521
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