Metabolic Reprogramming and Validation of Hyperpolarized (13)C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor

BACKGROUND: The treatment of prostate cancer has been impeded by the lack of both clinically relevant disease models and metabolic markers that track tumor progression. Hyperpolarized (HP) (13)C MR spectroscopy has emerged as a new technology to investigate the metabolic shifts in prostate cancer. I...

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Main Authors: Keshari, Kayvan R., Sriram, Renuka, Van Criekinge, Mark, Wilson, David M., Wang, Zhen J., Vigneron, Daniel B., Peehl, Donna M., Kurhanewicz, John
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976546/
https://ncbi.nlm.nih.gov/pubmed/23532911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22665
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