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Metabolic Reprogramming and Validation of Hyperpolarized (13)C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor

BACKGROUND: The treatment of prostate cancer has been impeded by the lack of both clinically relevant disease models and metabolic markers that track tumor progression. Hyperpolarized (HP) (13)C MR spectroscopy has emerged as a new technology to investigate the metabolic shifts in prostate cancer. I...

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Autors principals: Keshari, Kayvan R., Sriram, Renuka, Van Criekinge, Mark, Wilson, David M., Wang, Zhen J., Vigneron, Daniel B., Peehl, Donna M., Kurhanewicz, John
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976546/
https://ncbi.nlm.nih.gov/pubmed/23532911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22665
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