Elevated Tumor Lactate and Efflux in High-grade Prostate Cancer demonstrated by Hyperpolarized (13)C Magnetic Resonance Spectroscopy of Prostate Tissue Slice Cultures

Non-invasive assessment of the biological aggressiveness of prostate cancer (PCa) is needed for men with localized disease. Hyperpolarized (HP) (13)C magnetic resonance (MR) spectroscopy is a powerful approach to image metabolism, specifically the conversion of HP [1-(13)C]pyruvate to [1-(13)C]lacta...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Sriram, Renuka, Van Criekinge, Mark, DeLos Santos, Justin, Ahamed, Fayyaz, Qin, Hecong, Nolley, Rosalie, DeLos Santos, Romelyn, Tabatabai, Z. Laura, Bok, Robert A., Keshari, Kayvan R., Vigneron, Daniel B., Peehl, Donna M., Kurhanewicz, John
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7139946/
https://ncbi.nlm.nih.gov/pubmed/32110965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12030537
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