Metabolic Reprogramming and Validation of Hyperpolarized (13)C Lactate as a Prostate Cancer Biomarker Using a Human Prostate Tissue Slice Culture Bioreactor

BACKGROUND: The treatment of prostate cancer has been impeded by the lack of both clinically relevant disease models and metabolic markers that track tumor progression. Hyperpolarized (HP) (13)C MR spectroscopy has emerged as a new technology to investigate the metabolic shifts in prostate cancer. I...

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Bibliographic Details
Main Authors: Keshari, Kayvan R., Sriram, Renuka, Van Criekinge, Mark, Wilson, David M., Wang, Zhen J., Vigneron, Daniel B., Peehl, Donna M., Kurhanewicz, John
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976546/
https://ncbi.nlm.nih.gov/pubmed/23532911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22665
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