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De novo synthesis of a narrow size distribution low-molecular-weight heparin

Heparin, a commonly used anticoagulant drug, is a mixture of highly sulfated polysaccharides with various molecular weights (MWs). The unique sulfation pattern dictates the anticoagulant activity of heparin. Commercial heparins are categorized into three forms according to their average MW: unfracti...

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Bibliografische gegevens
Hoofdauteurs: Chandarajoti, Kasemsiri, Xu, Yongmei, Sparkenbaugh, Erica, Key, Nigel S, Pawlinski, Rafal, Liu, Jian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976284/
https://ncbi.nlm.nih.gov/pubmed/24626379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu016
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