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De novo synthesis of a narrow size distribution low-molecular-weight heparin

Heparin, a commonly used anticoagulant drug, is a mixture of highly sulfated polysaccharides with various molecular weights (MWs). The unique sulfation pattern dictates the anticoagulant activity of heparin. Commercial heparins are categorized into three forms according to their average MW: unfracti...

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Detalhes bibliográficos
Main Authors: Chandarajoti, Kasemsiri, Xu, Yongmei, Sparkenbaugh, Erica, Key, Nigel S, Pawlinski, Rafal, Liu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976284/
https://ncbi.nlm.nih.gov/pubmed/24626379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu016
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