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De novo synthesis of a narrow size distribution low-molecular-weight heparin

Heparin, a commonly used anticoagulant drug, is a mixture of highly sulfated polysaccharides with various molecular weights (MWs). The unique sulfation pattern dictates the anticoagulant activity of heparin. Commercial heparins are categorized into three forms according to their average MW: unfracti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chandarajoti, Kasemsiri, Xu, Yongmei, Sparkenbaugh, Erica, Key, Nigel S, Pawlinski, Rafal, Liu, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3976284/
https://ncbi.nlm.nih.gov/pubmed/24626379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwu016
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