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Thrombospondin-2 overexpression in the skin of transgenic mice reduces the susceptibility to chemically-induced multistep skin carcinogenesis
BACKGROUND: We have previously reported stromal upregulation of the endogenous angiogenesis inhibitor thrombospondin-2 (TSP-2) during multistep carcinogenesis, and we found accelerated and enhanced skin angiogenesis and carcinogenesis in TSP-2 deficient mice. GOALS: To investigate whether enhanced l...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3975683/ https://ncbi.nlm.nih.gov/pubmed/24507936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2014.01.002 |
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