Overexpression of Thrombospondin-1 Decreases Angiogenesis and Inhibits the Growth of Human Cutaneous Squamous Cell Carcinomas

The function of the endogenous angiogenesis inhibitor thrombospondin-1 (TSP-1) in epithelial tumor development has remained controversial. We studied the in vitro growth characteristics and the in vivo tumor xenograft growth of the human squamous cell carcinoma cell lines A431 and SCC-13, stably tra...

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Main Authors: Streit, Michael, Velasco, Paula, Brown, Lawrence F., Skobe, Mihaela, Richard, Lisa, Riccardi, Lucia, Lawler, Jack, Detmar, Michael
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 1999
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866855/
https://ncbi.nlm.nih.gov/pubmed/10433937
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