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Expression of Vascular Endothelial Growth Factor Induces an Invasive Phenotype in Human Squamous Cell Carcinomas

Inhibition of the vascular endothelial growth factor (VEGF) receptor Flk-1 has been shown to prevent invasion of experimental squamous cell carcinomas (SCC). To directly investigate the role of VEGF in tumor invasion, we stably transfected human SCC-13 cells, which are characterized by a noninvasive...

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Autors principals: Detmar, Michael, Velasco, Paula, Richard, Lisa, Claffey, Kevin P., Streit, Michael, Riccardi, Lucia, Skobe, Mihaela, Brown, Lawrence F.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868649/
https://ncbi.nlm.nih.gov/pubmed/10623663
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