Expression of the Type-1 Repeats of Thrombospondin-1 Inhibits Tumor Growth Through Activation of Transforming Growth Factor-β

In the present study, the type-1 repeats of thrombospondin-1 (TSP-1) were transfected into A431 cells. Expression of all three type-1 repeats (3TSR) and expression of just the second type-1 repeat containing the transforming growth factor (TGF)-β activating sequence KRFK (TSR2 + KRFK) significantly...

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Hlavní autoři: Yee, Karen O., Streit, Michael, Hawighorst, Thomas, Detmar, Michael, Lawler, Jack
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2004
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618557/
https://ncbi.nlm.nih.gov/pubmed/15277228
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