The Metastasis Suppressor, N-myc Downstream-regulated Gene 1 (NDRG1), Inhibits Stress-induced Autophagy in Cancer Cells

N-myc downstream regulated gene 1 (NDRG1) is a potent metastasis suppressor with an undefined role in the stress response. Autophagy is a pro-survival pathway and can be regulated via the protein kinase-like endoplasmic reticulum kinase (PERK)/eIF2α-mediated endoplasmic reticulum (ER) stress pathway...

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Hlavní autoři: Sahni, Sumit, Bae, Dong-Hun, Lane, Darius J. R., Kovacevic, Zaklina, Kalinowski, Danuta S., Jansson, Patric J., Richardson, Des R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3975018/
https://ncbi.nlm.nih.gov/pubmed/24532803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529511
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