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Inhibiting autophagy by shRNA knockdown: Cautions and recommendations

A glance through Autophagy or any other journal in this field shows that it is very common to block autophagy by RNA interference-based knockdown of ATG mRNAs in mammalian cell lines. Our lab’s experience is that this approach can easily make for failed experiments because good knockdown of even ess...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Staskiewicz, Leah, Thorburn, Jacqueline, Morgan, Michael J, Thorburn, Andrew
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974882/
https://ncbi.nlm.nih.gov/pubmed/23800703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24895
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